| Protein Name | killer cell lectin-like receptor subfamily K, member 1 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 27007 |
| Gene Symbol | Klrk1 |
| UniProt | O54709 (NKG2D_MOUSE), Q3TCW7 (Q3TCW7_MOUSE), Q4FJM0 (Q4FJM0_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
80
Total Number of Articles : 95 |
Description |
killer cell lectin-like receptor subfamily K, member 1 |
| Gene Summary |
Enables several functions, including MHC class I protein binding activity; MHC class Ib receptor activity; and identical protein binding activity. Involved in positive regulation of natural killer cell mediated cytotoxicity. Acts upstream of or within several processes, including positive regulation of biosynthetic process; response to bacterium; and stimulatory C-type lectin receptor signaling pathway. Located in external side of plasma membrane. Human ortholog(s) of this gene implicated in HTLV-1-associated myelopathy/tropical spastic paraparesis. Orthologous to several human genes including KLRK1 (killer cell lectin like receptor K1). [provided by Alliance of Genome Resources, Jul 2025] |
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| Properties | |