| Protein Name | LYN proto-oncogene, Src family tyrosine kinase |
|---|---|
| Organism | Mus musculus |
| Gene ID | 17096 |
| Gene Symbol | Lyn |
| UniProt | P25911 (LYN_MOUSE), Q3TCS3 (Q3TCS3_MOUSE), Q3U6Q5 (Q3U6Q5_MOUSE), Q8CEI0 (Q8CEI0_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
96
Total Number of Articles : 134 |
Description |
LYN proto-oncogene, Src family tyrosine kinase |
| Gene Summary |
Enables SH3 domain binding activity and non-membrane spanning protein tyrosine kinase activity. Involved in several processes, including immune response-regulating signaling pathway; immune system development; and regulation of signal transduction. Acts upstream of or within several processes, including B cell receptor signaling pathway; peptidyl-tyrosine phosphorylation; and regulation of release of sequestered calcium ion into cytosol. Located in several cellular components, including membrane raft; nucleus; and plasma membrane. Part of protein-containing complex. Is expressed in several structures, including alimentary system; genitourinary system; hemolymphoid system gland; liver and biliary system; and nervous system. Used to study systemic lupus erythematosus. Orthologous to human LYN (LYN proto-oncogene, Src family tyrosine kinase). [provided by Alliance of Genome Resources, Apr 2022] |
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