| Protein Name | dickkopf WNT signaling pathway inhibitor 1 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 13380 |
| Gene Symbol | Dkk1 |
| UniProt | O54908 (DKK1_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
88
Total Number of Articles : 97 |
Description |
dickkopf WNT signaling pathway inhibitor 1 |
| Gene Summary |
Predicted to enable co-receptor binding activity; low-density lipoprotein particle receptor binding activity; and receptor antagonist activity. Involved in several processes, including motor learning; negative regulation of cellular component organization; and regulation of gene expression. Acts upstream of or within several processes, including Wnt signaling pathway involved in somitogenesis; embryonic morphogenesis; and negative regulation of signal transduction. Predicted to be located in extracellular region and plasma membrane. Predicted to be active in extracellular space. Is expressed in several structures, including alimentary system; embryo mesenchyme; eye; genitourinary system; and nervous system. Human ortholog(s) of this gene implicated in anodontia. Orthologous to human DKK1 (dickkopf WNT signaling pathway inhibitor 1). [provided by Alliance of Genome Resources, Jul 2025] |
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| Properties | |