Protein Name general transcription factor IIA subunit 1
Organism Homo sapiens
Gene ID 2957
Gene Symbol

GTF2A1

UniProt P52655 (TF2AA_HUMAN)
Relationships Total Number of functionally related compound(s) : 25
Total Number of Articles : 23
Description

general transcription factor IIA subunit 1

Gene Summary

Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A; MIM 180660) and several general initiation factors (summarized by DeJong and Roeder, 1993 [PubMed 8224848]). One of these factors is TFIIA, which when purified from HeLa extracts consists of 35-, 19-, and 12-kD subunits.[supplied by OMIM, Jul 2010]

synonyms
  • transcription initiation factor IIA subunit 1
  • TFIIA alpha/beta subunits
  • general transcription factor IIA 1
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Properties