| Protein Name | autophagy related 3 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 67841 |
| Gene Symbol | Atg3 |
| UniProt | Q9CPX6 (ATG3_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
25
Total Number of Articles : 22 |
Description |
autophagy related 3 |
| Gene Summary |
Enables Atg12 transferase activity and Atg8-family ligase activity. Involved in autophagosome assembly; mitochondrial fragmentation involved in apoptotic process; and regulation of cilium assembly. Acts upstream of or within macroautophagy and negative regulation of phagocytosis. Predicted to be part of Atg12-Atg5-Atg16 complex and cytoplasmic ubiquitin ligase complex. Predicted to be active in cytosol and phagophore assembly site. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and integumental system. Orthologous to human ATG3 (autophagy related 3). [provided by Alliance of Genome Resources, Jun 2025] |
| synonyms |
|
| Properties | |