Protein Name metadherin
Organism Homo sapiens
Gene ID 92140
Gene Symbol

MTDH

UniProt Q86UE4 (LYRIC_HUMAN), A0A024R9D2 (A0A024R9D2_HUMAN)
Relationships Total Number of functionally related compound(s) : 129
Total Number of Articles : 162
Description

metadherin

Gene Summary

Enables NF-kappaB binding activity; double-stranded RNA binding activity; and transcription coactivator activity. Involved in several processes, including lipopolysaccharide-mediated signaling pathway; positive regulation of intracellular signal transduction; and regulation of DNA-templated transcription. Located in endoplasmic reticulum; nuclear lumen; and perinuclear region of cytoplasm. Implicated in hepatocellular carcinoma. [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • protein LYRIC
  • 3D3/LYRIC
  • astrocyte elevated gene 1
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Properties