| Protein Name | purinergic receptor P2Y12 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 64803 |
| Gene Symbol | P2ry12 |
| UniProt | Q9EPX4 (P2Y12_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
62
Total Number of Articles : 68 |
Description |
purinergic receptor P2Y12 |
| Gene Summary |
Enables G protein-coupled ADP receptor activity. Involved in several processes, including G protein-coupled receptor signaling pathway; monoatomic cation transmembrane transport; and positive regulation of cellular component biogenesis. Located in basal plasma membrane; caveola; and external side of plasma membrane. Used to study abdominal aortic aneurysm and thrombosis. Human ortholog(s) of this gene implicated in asthma; cerebrovascular disease; peripheral artery disease; platelet-type bleeding disorder 8; and type 2 diabetes mellitus. Orthologous to human P2RY12 (purinergic receptor P2Y12). [provided by Alliance of Genome Resources, Jul 2025] |
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