Protein Name neurotrophin 5
Organism Mus musculus
Gene ID 78405
Gene Symbol

Ntf5

UniProt Q80VU4 (NTF4_MOUSE)
Relationships Total Number of functionally related compound(s) : 30
Total Number of Articles : 25
Description

neurotrophin 5

Gene Summary

This gene encodes a secreted protein belonging to the neurotrophin family of structurally related molecules that play a crucial role in the control of neuronal numbers and of dendritic growth. The encoded preproprotein undergoes post-translational processing to generate non-covalently associated homodimeric functional protein. Mice deficient in the encoded protein exhibit a loss of sensory neurons in the nodose-petrosal and geniculate ganglia, have deficits in long-term memory and hippocampal long-lasting long-term potentiation. [provided by RefSeq, Oct 2015]

synonyms
  • neurotrophin-4
  • neutrophic factor 4
  • 2900040K06Rik
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Properties