Protein Name trophoblast glycoprotein
Organism Homo sapiens
Gene ID 7162
Gene Symbol

TPBG

UniProt Q13641 (TPBG_HUMAN)
Relationships Total Number of functionally related compound(s) : 24
Total Number of Articles : 11
Description

trophoblast glycoprotein

Gene Summary

This gene encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. The encoded protein is an oncofetal antigen that is specific to trophoblast cells. In adults this protein is highly expressed in many tumor cells and is associated with poor clinical outcome in numerous cancers. Alternate splicing in the 5' UTR results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2009]

synonyms
  • trophoblast glycoprotein
  • 5T4 oncofetal antigen
  • 5T4 oncofetal trophoblast glycoprotein
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Properties