Protein Name arrestin, beta 1
Organism Rattus norvegicus
Gene ID 25387
Gene Symbol

Arrb1

UniProt P29066 (ARRB1_RAT)
Relationships Total Number of functionally related compound(s) : 33
Total Number of Articles : 26
Description

arrestin, beta 1

Gene Summary

Enables several functions, including AP-2 adaptor complex binding activity; G protein-coupled receptor binding activity; and arrestin family protein binding activity. Involved in several processes, including regulation of ERK1 and ERK2 cascade; regulation of apoptotic process; and regulation of cellular protein metabolic process. Located in several cellular components, including basolateral plasma membrane; dendritic spine; and postsynaptic density. Used to study congestive heart failure. Biomarker of colitis. Orthologous to human ARRB1 (arrestin beta 1). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • beta-arrestin-1
  • BARRES
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Properties