Protein Name hypoxia inducible factor 1 subunit alpha inhibitor
Organism Homo sapiens
Gene ID 55662
Gene Symbol

HIF1AN

UniProt Q9NWT6 (HIF1N_HUMAN)
Relationships Total Number of functionally related compound(s) : 61
Total Number of Articles : 64
Description

hypoxia inducible factor 1 subunit alpha inhibitor

Gene Summary

Enables several functions, including 2-oxoglutarate-dependent dioxygenase activity; NF-kappaB binding activity; and transition metal ion binding activity. Involved in several processes, including negative regulation of Notch signaling pathway; negative regulation of transcription from RNA polymerase II promoter in response to hypoxia; and protein hydroxylation. Located in cytosol; nucleoplasm; and perinuclear region of cytoplasm. Colocalizes with nucleus. [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • hypoxia-inducible factor 1-alpha inhibitor
  • FIH-1
  • factor inhibiting HIF-1
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Properties