Protein Name natriuretic peptide type A
Organism Mus musculus
Gene ID 230899
Gene Symbol

Nppa

UniProt P05125 (ANF_MOUSE)
Relationships Total Number of functionally related compound(s) : 193
Total Number of Articles : 233
Description

natriuretic peptide type A

Gene Summary

This gene encodes members of the natriuretic family of peptides that play an important role in the control of extracellular fluid volume and electrolyte homeostasis. The encoded protein precursor undergoes proteolytic processing to generate multiple functional peptides. Mice lacking the encoded peptides exhibit salt-sensitive hypertension. The transgenic overexpression of the encoded peptides in mice decreases arterial blood pressure without inducing diuresis and natriuresis. This gene is located adjacent to another member of the natriuretic family of peptides on chromosome 4. [provided by RefSeq, Oct 2015]

synonyms
  • natriuretic peptides A
  • atrial natriuretic factor prohormone
  • atrial natriuretic peptide prohormone
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Properties