Protein Name SOS Ras/Rac guanine nucleotide exchange factor 1
Organism Homo sapiens
Gene ID 6654
Gene Symbol

SOS1

UniProt Q07889 (SOS1_HUMAN), G5E9C8 (G5E9C8_HUMAN)
Relationships Total Number of functionally related compound(s) : 120
Total Number of Articles : 139
Description

SOS Ras/Rac guanine nucleotide exchange factor 1

Gene Summary

This gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4. [provided by RefSeq, Jul 2008]

synonyms
  • son of sevenless homolog 1
  • gingival fibromatosis, hereditary, 1
  • guanine nucleotide exchange factor
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Properties