Protein Name | MYB proto-oncogene like 2 |
---|---|
Organism | Homo sapiens |
Gene ID | 4605 |
Gene Symbol | MYBL2 |
UniProt | P10244 (MYBB_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
42
Total Number of Articles : 40 |
Description |
MYB proto-oncogene like 2 |
Gene Summary |
The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013] |
synonyms |
|
Properties | |