Protein Name MYB proto-oncogene like 2
Organism Homo sapiens
Gene ID 4605
Gene Symbol

MYBL2

UniProt P10244 (MYBB_HUMAN)
Relationships Total Number of functionally related compound(s) : 42
Total Number of Articles : 40
Description

MYB proto-oncogene like 2

Gene Summary

The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013]

synonyms
  • myb-related protein B
  • myb-like protein 2
  • v-myb avian myeloblastosis viral oncogene homolog-like 2
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Properties