Protein Name lipoprotein(a)
Organism Homo sapiens
Gene ID 4018
Gene Symbol


UniProt -
Relationships Total Number of functionally related compound(s) : 544
Total Number of Articles : 1318


Gene Summary

The protein encoded by this gene is a serine proteinase that inhibits the activity of tissue-type plasminogen activator I. The encoded protein constitutes a substantial portion of lipoprotein(a) and is proteolytically cleaved, resulting in fragments that attach to atherosclerotic lesions and promote thrombogenesis. Elevated plasma levels of this protein are linked to atherosclerosis. Depending on the individual, the encoded protein contains 2-43 copies of kringle-type domains. The allele represented here contains 15 copies of the kringle-type repeats and corresponds to that found in the reference genome sequence. [provided by RefSeq, Dec 2009]

  • apolipoprotein(a)
  • antiangiogenic AK38 protein
  • apo(a)
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