| Protein Name | amyloid beta precursor like protein 1 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 333 |
| Gene Symbol | APLP1 |
| UniProt | P51693 (APLP1_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
21
Total Number of Articles : 20 |
Description |
amyloid beta precursor like protein 1 |
| Gene Summary |
This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] |
| synonyms |
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| Properties | |