| Protein Name | integrin subunit alpha M |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 25021 |
| Gene Symbol | Itgam |
| UniProt | Q9JI30 (Q9JI30_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
150
Total Number of Articles : 167 |
Description |
integrin subunit alpha M |
| Gene Summary |
Predicted to enable several functions, including complement component C3b binding activity; heparan sulfate proteoglycan binding activity; and heparin binding activity. Predicted to contribute to cargo receptor activity. Involved in several processes, including response to Gram-positive bacterium; response to curcumin; and response to ischemia. Located in cell surface. Used to study mesangial proliferative glomerulonephritis; neutropenia; and transient cerebral ischemia. Biomarker of brain ischemia; diabetic retinopathy; transient cerebral ischemia; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in lupus nephritis; persistent fetal circulation syndrome; and pre-eclampsia. Orthologous to human ITGAM (integrin subunit alpha M). [provided by Alliance of Genome Resources, Jul 2025] |
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