| Protein Name | thyroid hormone receptor beta |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 24831 |
| Gene Symbol | Thrb |
| UniProt | F1LQ07 (F1LQ07_RAT), Q3HW36 (Q3HW36_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
54
Total Number of Articles : 49 |
Description |
thyroid hormone receptor beta |
| Gene Summary |
Enables double-stranded DNA binding activity; identical protein binding activity; and nuclear receptor activity. Involved in several processes, including positive regulation of chondrocyte differentiation; positive regulation of ossification; and regulation of lipid metabolic process. Predicted to be located in nuclear body. Predicted to be part of RNA polymerase II transcription regulator complex. Predicted to be active in nucleus. Used to study breast cancer. Human ortholog(s) of this gene implicated in several diseases, including cervix uteri carcinoma in situ; prostate cancer; renal cell carcinoma; selective pituitary thyroid hormone resistance; and thyroid hormone resistance syndrome. Orthologous to human THRB (thyroid hormone receptor beta). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |