CPRiL

Protein Name	ATP binding cassette subfamily G member 2
Organism	Rattus norvegicus
Gene ID	312382
Gene Symbol	Abcg2
UniProt	Q80W57 (ABCG2_RAT)
Relationships	Total Number of functionally related compound(s) : 69 Total Number of Articles : 57
Description	ATP binding cassette subfamily G member 2
Gene Summary	Enables several functions, including cytoskeletal protein binding activity; efflux transmembrane transporter activity; and xenobiotic transmembrane transporter activity. Involved in several processes, including cellular response to lipid; embryonic process involved in female pregnancy; and urate salt excretion. Located in external side of apical plasma membrane and nucleus. Biomarker of diabetes mellitus; secondary hyperparathyroidism; status epilepticus; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in gout; hematologic cancer (multiple); renal cell carcinoma; and toxic encephalopathy. Orthologous to human ABCG2 (ATP binding cassette subfamily G member 2 (Junior blood group)). [provided by Alliance of Genome Resources, Apr 2022]
synonyms	broad substrate specificity ATP-binding cassette transporter ABCG2 ATP binding cassette subfamily G member 2 (Junior blood group) ATP-binding cassette protein G2 ATP-binding cassette sub-family G member 2 ATP-binding cassette, sub-family G (WHITE), member 2 ATP-binding cassette, subfamily G (WHITE), member 2 breast cancer resistance protein 1 homolog urate exporter BCRP1 Bcrp Click to show/hide the synonyms
Properties