| Protein Name | DNA methyltransferase 3 beta |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 444985 |
| Gene Symbol | Dnmt3b |
| UniProt | Q1LZ51 (Q1LZ51_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
28
Total Number of Articles : 20 |
Description |
DNA methyltransferase 3 beta |
| Gene Summary |
Enables chromatin binding activity. Involved in several processes, including cellular response to dexamethasone stimulus; cellular response to hyperoxia; and response to vitamin A. Predicted to be located in chromosome, centromeric region; heterochromatin; and nucleoplasm. Predicted to be part of catalytic complex. Predicted to be active in nucleus. Biomarker of anxiety disorder; congenital heart disease; fetal alcohol spectrum disorder; hepatocellular carcinoma; and prostatitis. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); carcinoma (multiple); facioscapulohumeral muscular dystrophy 4; immunodeficiency-centromeric instability-facial anomalies syndrome 1; and thymoma. Orthologous to human DNMT3B (DNA methyltransferase 3 beta). [provided by Alliance of Genome Resources, Jun 2025] |
| synonyms |
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| Properties | |