Protein Name 1-phosphatidylinositol-4-phosphate 5-kinase
Organism Saccharomyces cerevisiae S288C
Gene ID 851789
Gene Symbol

MSS4

UniProt P38994 (MSS4_YEAST)
Relationships Total Number of functionally related compound(s) : 24
Total Number of Articles : 23
Description

1-phosphatidylinositol-4-phosphate 5-kinase

Gene Summary

Enables 1-phosphatidylinositol-4-phosphate 5-kinase activity; phosphatidylinositol-3-phosphate binding activity; and phosphatidylinositol-4-phosphate binding activity. Involved in ascospore-type prospore assembly and phosphatidylinositol phosphate biosynthetic process. Located in nucleus and plasma membrane. Used to study cancer. Human ortholog(s) of this gene implicated in lethal congenital contracture syndrome 3. Orthologous to several human genes including PIP5K1A (phosphatidylinositol-4-phosphate 5-kinase type 1 alpha); PIP5K1C (phosphatidylinositol-4-phosphate 5-kinase type 1 gamma); and PIP4K2A (phosphatidylinositol-5-phosphate 4-kinase type 2 alpha). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • 1-phosphatidylinositol-4-phosphate 5-kinase
  • YDR208W
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Properties