Protein Name SRY-box transcription factor 4
Organism Homo sapiens
Gene ID 6659
Gene Symbol

SOX4

UniProt Q06945 (SOX4_HUMAN)
Relationships Total Number of functionally related compound(s) : 84
Total Number of Articles : 98
Description

SRY-box transcription factor 4

Gene Summary

This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein. [provided by RefSeq, Jul 2008]

synonyms
  • transcription factor SOX-4
  • SRY (sex determining region Y)-box 4
  • SRY-box 4
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Properties