| Protein Name | interleukin 4 receptor, alpha |
|---|---|
| Organism | Mus musculus |
| Gene ID | 16190 |
| Gene Symbol | Il4ra |
| UniProt | P16382 (IL4RA_MOUSE), Q3U905 (Q3U905_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
82
Total Number of Articles : 84 |
Description |
interleukin 4 receptor, alpha |
| Gene Summary |
Predicted to enable cytokine receptor activity. Involved in positive regulation of chemokine production; positive regulation of cold-induced thermogenesis; and positive regulation of macrophage activation. Acts upstream of or within several processes, including defense response to protozoan; negative regulation of T-helper 1 cell differentiation; and positive regulation of immune effector process. Predicted to be located in several cellular components, including centriolar satellite; extracellular space; and nucleoplasm. Predicted to be part of receptor complex. Is expressed in several structures, including adrenal medulla; early conceptus; hemolymphoid system; medulla oblongata basal plate mantle layer; and reproductive system. Used to study asthma. Human ortholog(s) of this gene implicated in several diseases, including acne; allergic conjunctivitis; autoimmune disease (multiple); human immunodeficiency virus infectious disease; and renal tuberculosis. Orthologous to human IL4R (interleukin 4 receptor). [provided by Alliance of Genome Resources, Apr 2022] |
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