Protein Name RUNX family transcription factor 2
Organism Rattus norvegicus
Gene ID 367218
Gene Symbol

Runx2

UniProt F1M9C5 (F1M9C5_RAT)
Relationships Total Number of functionally related compound(s) : 243
Total Number of Articles : 315
Description

RUNX family transcription factor 2

Gene Summary

Enables DNA-binding transcription factor binding activity; general transcription initiation factor binding activity; and histone deacetylase binding activity. Involved in cellular response to fibroblast growth factor stimulus; osteoblast differentiation; and positive regulation of ossification. Located in nucleus. Human ortholog(s) of this gene implicated in cleidocranial dysplasia and metaphyseal dysplasia-maxillary hypoplasia-brachydacty syndrome. Orthologous to human RUNX2 (RUNX family transcription factor 2). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • runt-related transcription factor 2
  • core-binding factor subunit alpha-1
  • osteoblast-specific transcription factor 2
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Properties