| Protein Name | RUNX family transcription factor 2 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 367218 |
| Gene Symbol | Runx2 |
| UniProt | F1M9C5 (F1M9C5_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
243
Total Number of Articles : 315 |
Description |
RUNX family transcription factor 2 |
| Gene Summary |
Enables DNA-binding transcription factor binding activity; general transcription initiation factor binding activity; and histone deacetylase binding activity. Involved in several processes, including bone regeneration; cellular response to hyperoxia; and cellular response to parathyroid hormone stimulus. Located in nucleus. Biomarker of glucocorticoid-induced osteoporosis; metabolic acidosis; osteoporosis; and type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in cleidocranial dysplasia; lung non-small cell carcinoma; metaphyseal dysplasia-maxillary hypoplasia-brachydactyly syndrome; and osteonecrosis. Orthologous to human RUNX2 (RUNX family transcription factor 2). [provided by Alliance of Genome Resources, Jul 2025] |
| synonyms |
|
| Properties | |