| Protein Name | mucin 1, transmembrane |
|---|---|
| Organism | Mus musculus |
| Gene ID | 17829 |
| Gene Symbol | Muc1 |
| UniProt | Q02496 (MUC1_MOUSE), A0A0R4J0H1 (A0A0R4J0H1_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
169
Total Number of Articles : 178 |
Description |
mucin 1, transmembrane |
| Gene Summary |
Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; p53 binding activity; and transcription coregulator activity. Predicted to be involved in several processes, including DNA damage response, signal transduction by p53 class mediator; negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; and regulation of transcription, DNA-templated. Located in apical plasma membrane and cell surface. Is expressed in several structures, including brain; exocrine gland; genitourinary system; gut; and respiratory system. Human ortholog(s) of this gene implicated in several diseases, including allergic rhinitis; biliary tract benign neoplasm; dry eye syndrome; familial juvenile hyperuricemic nephropathy; and pancreatic cancer (multiple). Orthologous to human MUC1 (mucin 1, cell surface associated). [provided by Alliance of Genome Resources, Apr 2022] |
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