Protein Name sialic acid binding Ig-like lectin G
Organism Mus musculus
Gene ID 243958
Gene Symbol

Siglecg

UniProt Q80ZE3 (SIG10_MOUSE), Q8BY18 (Q8BY18_MOUSE)
Relationships Total Number of functionally related compound(s) : 6
Total Number of Articles : 16
Description

sialic acid binding Ig-like lectin G

Gene Summary

Predicted to enable SH2 domain binding activity; phosphatase binding activity; and sialic acid binding activity. Involved in several processes, including negative regulation of calcium-mediated signaling; negative regulation of inflammatory response to wounding; and regulation of B cell proliferation. Acts upstream of or within hematopoietic progenitor cell differentiation. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in liver and thymus primordium. Orthologous to several human genes including SIGLEC10 (sialic acid binding Ig like lectin 10) and SIGLEC11 (sialic acid binding Ig like lectin 11). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • sialic acid-binding Ig-like lectin 10
  • sialic acid binding Ig-like lectin 10
  • siglec-10
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Properties