Protein Name Death regulator Nedd2-like caspase
Organism Drosophila melanogaster
Gene ID 39173
Gene Symbol

Dronc

UniProt Q9XYF4 (DRONC_DROME)
Relationships Total Number of functionally related compound(s) : 17
Total Number of Articles : 21
Description

Death regulator Nedd2-like caspase

Gene Summary

Enables cysteine-type endopeptidase activity involved in apoptotic signaling pathway and protein homodimerization activity. Involved in several processes, including positive regulation of cell death; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; and programmed cell death involved in cell development. Located in cytoplasm; nucleus; and plasma membrane. Part of apoptosome. Is expressed in several structures, including extended germ band embryo; eye disc; foregut primordium; germline cyst; and gut section. Used to study testicular cancer. Orthologous to human CASP2 (caspase 2). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • death regulator Nedd2-like caspase
  • CG8091-PA
  • Caspase-9-like
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Properties