Protein Name | interferon lambda 3 |
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Organism | Homo sapiens |
Gene ID | 282617 |
Gene Symbol | IFNL3 |
UniProt | Q8IZI9 (IFNL3_HUMAN), A0A0C4DGW8 (A0A0C4DGW8_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
101
Total Number of Articles : 407 |
Description |
interferon lambda 3 |
Gene Summary |
This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq, Jul 2008] |
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