CPRiL

USP7

ubiquitin specific peptidase 7

The protein encoded by this gene belongs to the peptidase C19 family, which includes ubiquitinyl hydrolases. This protein deubiquitinates target proteins such as p53 (a tumor suppressor protein) and WASH (essential for endosomal protein recycling), and regulates their activities by counteracting the opposing ubiquitin ligase activity of proteins such as HDM2 and TRIM27, involved in the respective process. Mutations in this gene have been implicated in a neurodevelopmental disorder. [provided by RefSeq, Mar 2016]

• ubiquitin carboxyl-terminal hydrolase 7
• Chromosome 16p13.2 deletion syndrome
• Herpes virus-associated ubiquitin-specific protease
deubiquitinating enzyme 7
ubiquitin specific peptidase 7 (herpes virus-associated)
ubiquitin specific protease 7 (herpes virus-associated)
ubiquitin thioesterase 7
ubiquitin-specific-processing protease 7
C16DELp13.2
DEL16P13.2
HAFOUS
HAUSP
TEF1