Protein Name paired-like homeodomain 3
Organism Rattus norvegicus
Gene ID 29609
Gene Symbol

Pitx3

UniProt P81062 (PITX3_RAT)
Relationships Total Number of functionally related compound(s) : 10
Total Number of Articles : 15
Description

paired-like homeodomain 3

Gene Summary

Enables DNA-binding transcription factor activity. Involved in several processes, including cellular response to glial cell derived neurotrophic factor; positive regulation of cell proliferation in midbrain; and response to methamphetamine hydrochloride. Located in chromatin. Human ortholog(s) of this gene implicated in anterior segment dysgenesis; anterior segment dysgenesis 1; cataract; cataract 11 multiple types; and cataract 9 multiple types. Orthologous to human PITX3 (paired like homeodomain 3). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • pituitary homeobox 3
  • homeobox protein PITX3
  • homeobox protein PTX3
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Properties