Protein Name regulatory protein (NPR1)
Organism Arabidopsis thaliana
Gene ID 842733
Gene Symbol

NPR1

UniProt P93002 (NPR1_ARATH), B2BDI6 (B2BDI6_ARATH)
Relationships Total Number of functionally related compound(s) : 92
Total Number of Articles : 232
Description

regulatory protein (NPR1)

Gene Summary

This gene is a key regulator of the salicylic acid (SA)-mediated systemic acquired resistance (SAR) pathway. It is similar to the transcription factor inhibitor I kappa B, and contains ankyrin repeats. It confers resistance to the pathogens Pseudomonas syringae and Peronospora parasitica in a dosage-dependent fashion. Although transgenic Arabidopsis plants overexpressing NPR1 acquire enhanced sensitivity to SA and (benzothiadiazole) BTH, they display no obvious detrimental morphological changes and do not have elevated pathogenesis-related gene expression until activated by inducers or pathogens.

synonyms
  • regulatory protein (NPR1)
  • AT1G64280
  • ARABIDOPSIS NONEXPRESSER OF PR GENES 1
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Properties