Protein Name glutamate receptor, ionotropic, NMDA2C (epsilon 3)
Organism Mus musculus
Gene ID 14813
Gene Symbol

Grin2c

UniProt Q01098 (NMDE3_MOUSE), A2A6S2 (A2A6S2_MOUSE)
Relationships Total Number of functionally related compound(s) : 39
Total Number of Articles : 52
Description

glutamate receptor, ionotropic, NMDA2C (epsilon 3)

Gene Summary

Enables NMDA glutamate receptor activity; monoatomic cation channel activity; and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Involved in regulation of synaptic plasticity. Acts upstream of or within several processes, including excitatory postsynaptic potential; neuromuscular process controlling balance; and protein localization to postsynaptic membrane. Located in postsynaptic membrane. Part of NMDA selective glutamate receptor complex. Is active in glutamatergic synapse and postsynaptic density membrane. Is expressed in several structures, including brain; colon; eye; gallbladder; and genitourinary system. Orthologous to human GRIN2C (glutamate ionotropic receptor NMDA type subunit 2C). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • glutamate receptor ionotropic, NMDA 2C
  • GluRepsilon3
  • N-methyl D-aspartate receptor subtype 2C
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Properties