| Protein Name | cell division cycle 42 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 12540 |
| Gene Symbol | Cdc42 |
| UniProt | P60766 (CDC42_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
150
Total Number of Articles : 204 |
Description |
cell division cycle 42 |
| Gene Summary |
Enables GTP-dependent protein binding activity; GTPase activity; and protein kinase binding activity. Involved in several processes, including dendritic spine morphogenesis; heart development; and positive regulation of cellular component organization. Acts upstream of or within several processes, including cellular response to type II interferon; filopodium assembly; and positive regulation of intracellular signal transduction. Located in several cellular components, including leading edge membrane; phagocytic vesicle; and storage vacuole. Is active in cell leading edge; glutamatergic synapse; and postsynapse. Is expressed in several structures, including alimentary system; brain; early conceptus; eye; and genitourinary system. Used to study cleft palate and microvillus inclusion disease. Human ortholog(s) of this gene implicated in fibrosarcoma. Orthologous to human CDC42 (cell division cycle 42). [provided by Alliance of Genome Resources, Jun 2025] |
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