Protein Name lysine demethylase 2B
Organism Homo sapiens
Gene ID 84678
Gene Symbol

KDM2B

UniProt Q8NHM5 (KDM2B_HUMAN), B4DSN4 (B4DSN4_HUMAN)
Relationships Total Number of functionally related compound(s) : 26
Total Number of Articles : 33
Description

lysine demethylase 2B

Gene Summary

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]

synonyms
  • lysine-specific demethylase 2B
  • CXXC-type zinc finger protein 2
  • F-box and leucine-rich repeat protein 10
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Properties