| Protein Name | apoptotic peptidase activating factor 1 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 78963 |
| Gene Symbol | Apaf1 |
| UniProt | Q9EPV5 (APAF_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
63
Total Number of Articles : 53 |
Description |
apoptotic peptidase activating factor 1 |
| Gene Summary |
Enables heat shock protein binding activity and identical protein binding activity. Involved in several processes, including cardiac muscle cell apoptotic process; cellular response to transforming growth factor beta stimulus; and response to hypoxia. Located in cytoplasm. Part of apoptosome. Biomarker of brain ischemia; colon cancer; middle cerebral artery infarction; and muscular atrophy. Orthologous to human APAF1 (apoptotic peptidase activating factor 1). [provided by Alliance of Genome Resources, Jul 2025] |
| synonyms |
|
| Properties | |