| Protein Name | serine/threonine kinase 3 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 6788 |
| Gene Symbol | STK3 |
| UniProt | Q13188 (STK3_HUMAN), A0A384MR07 (A0A384MR07_HUMAN), A0A087WZ06 (A0A087WZ06_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
28
Total Number of Articles : 34 |
Description |
serine/threonine kinase 3 |
| Gene Summary |
This gene encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase removes the inhibitory C-terminal portion. The N-terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] |
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| Properties | |