Protein Name lactase
Organism Homo sapiens
Gene ID 3938
Gene Symbol


UniProt P09848 (LPH_HUMAN)
Relationships Total Number of functionally related compound(s) : 376
Total Number of Articles : 596


Gene Summary

The protein encoded by this gene belongs to the glycosyl hydrolase 1 family of proteins. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme is integral to the plasma membrane and has both phlorizin hydrolase activity and lactase activity. Mutations in this gene are associated with congenital lactase deficiency. Polymorphisms in this gene are associated with lactase persistence, in which intestinal lactase activity persists at childhood levels into adulthood. [provided by RefSeq, Jan 2016]

  • lactase/phlorizin hydrolase
  • lactase-glycosylceramidase
  • lactase-phlorizin hydrolase-1
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