| Protein Name | O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) |
|---|---|
| Organism | Mus musculus |
| Gene ID | 108155 |
| Gene Symbol | Ogt |
| UniProt | Q8CGY8 (OGT1_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
79
Total Number of Articles : 116 |
Description |
O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) |
| Gene Summary |
Enables chromatin DNA binding activity and protein O-acetylglucosaminyltransferase activity. Involved in several processes, including circadian regulation of gene expression; positive regulation of cold-induced thermogenesis; and regulation of primary metabolic process. Acts upstream of or within protein O-linked glycosylation. Is active in glutamatergic synapse and nucleus. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Used to study congenital disorder of glycosylation. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 106. Orthologous to human OGT (O-linked N-acetylglucosamine (GlcNAc) transferase). [provided by Alliance of Genome Resources, Jun 2025] |
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