| Protein Name | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 6598 |
| Gene Symbol | SMARCB1 |
| UniProt | Q12824 (SNF5_HUMAN), G5E975 (G5E975_HUMAN), Q9H836 (Q9H836_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
66
Total Number of Articles : 99 |
Description |
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 |
| Gene Summary |
The protein encoded by this gene is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. This gene has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2015] |
| synonyms |
|
| Properties | |