Protein Name piezo-type mechanosensitive ion channel component 2
Organism Mus musculus
Gene ID 667742
Gene Symbol

Piezo2

UniProt Q8CD54 (PIEZ2_MOUSE), S4R2S0 (S4R2S0_MOUSE), E9QNW4 (E9QNW4_MOUSE)
Relationships Total Number of functionally related compound(s) : 17
Total Number of Articles : 13
Description

piezo-type mechanosensitive ion channel component 2

Gene Summary

Enables mechanosensitive monoatomic ion channel activity and monoatomic cation channel activity. Involved in detection of mechanical stimulus involved in sensory perception and monoatomic cation transport. Acts upstream of or within regulation of membrane potential. Located in cuticular plate; neuronal cell body membrane; and stereocilium. Is expressed in dorsal root ganglion; forelimb; lung; lung epithelium; and thoracic dorsal root ganglion. Human ortholog(s) of this gene implicated in distal arthrogryposis type 3 and distal arthrogryposis type 5. Orthologous to human PIEZO2 (piezo type mechanosensitive ion channel component 2). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • piezo-type mechanosensitive ion channel component 2
  • family with sequence similarity 38, member B
  • family with sequence similarity 38, member B2
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Properties