| Protein Name | laminin subunit alpha 5 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 3911 |
| Gene Symbol | LAMA5 |
| UniProt | O15230 (LAMA5_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
15
Total Number of Articles : 15 |
Description |
laminin subunit alpha 5 |
| Gene Summary |
This gene encodes one of the vertebrate laminin alpha chains. Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. The protein encoded by this gene is the alpha-5 subunit of of laminin-10 (laminin-511), laminin-11 (laminin-521) and laminin-15 (laminin-523). [provided by RefSeq, Jun 2013] |
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| Properties | |