| Protein Name | leucine rich repeat containing G protein-coupled receptor 5 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 8549 |
| Gene Symbol | LGR5 |
| UniProt | O75473 (LGR5_HUMAN), A0A0A8K8C7 (A0A0A8K8C7_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
99
Total Number of Articles : 107 |
Description |
leucine rich repeat containing G protein-coupled receptor 5 |
| Gene Summary |
The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015] |
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