Protein Name glycogen synthase kinase 3 beta
Organism Mus musculus
Gene ID 56637
Gene Symbol


Relationships Total Number of functionally related compound(s) : 814
Total Number of Articles : 1369

glycogen synthase kinase 3 beta

Gene Summary

Enables several functions, including beta-catenin binding activity; dynein complex binding activity; and protein kinase activity. Involved in several processes, including apoptotic signaling pathway; negative regulation of signal transduction; and regulation of gene expression. Acts upstream of or within several processes, including cellular response to hepatocyte growth factor stimulus; positive regulation of nitrogen compound metabolic process; and regulation of neuron projection development. Located in several cellular components, including dendritic shaft; glutamatergic synapse; and postsynaptic density. Part of Wnt signalosome; beta-catenin destruction complex; and ribonucleoprotein complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; immune system; and sensory organ. Human ortholog(s) of this gene implicated in Alzheimer's disease; amyotrophic lateral sclerosis; bipolar disorder; and schizophrenia. Orthologous to human GSK3B (glycogen synthase kinase 3 beta). [provided by Alliance of Genome Resources, Apr 2022]

  • glycogen synthase kinase-3 beta
  • serine/threonine-protein kinase GSK3B
  • 7330414F15Rik
Click to show/hide the synonyms