Protein Name reticulon 4
Organism Rattus norvegicus
Gene ID 83765
Gene Symbol

Rtn4

UniProt Q9JK11 (RTN4_RAT), Q6IRL3 (Q6IRL3_RAT), Q540J3 (Q540J3_RAT)
Relationships Total Number of functionally related compound(s) : 78
Total Number of Articles : 62
Description

reticulon 4

Gene Summary

Predicted to enable cadherin binding activity; protein homodimerization activity; and ubiquitin protein ligase binding activity. Involved in several processes, including negative regulation of neuron projection regeneration; nervous system development; and positive regulation of dopamine secretion. Located in several cellular components, including endoplasmic reticulum; myelin sheath; and neuronal cell body. Is integral component of endoplasmic reticulum membrane. Part of protein-containing complex. Is active in glutamatergic synapse. Is integral component of postsynaptic density membrane. Biomarker of visual epilepsy. Orthologous to human RTN4 (reticulon 4). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • reticulon-4
  • GLUT4 vesicle 20kDa protein
  • NI-220/250
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Properties