Protein Name | reticulon 4 |
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Organism | Rattus norvegicus |
Gene ID | 83765 |
Gene Symbol | Rtn4 |
UniProt | Q9JK11 (RTN4_RAT), Q6IRL3 (Q6IRL3_RAT), Q540J3 (Q540J3_RAT) |
Relationships |
Total Number of functionally related compound(s) :
78
Total Number of Articles : 62 |
Description |
reticulon 4 |
Gene Summary |
Predicted to enable cadherin binding activity; protein homodimerization activity; and ubiquitin protein ligase binding activity. Involved in several processes, including negative regulation of neuron projection regeneration; nervous system development; and positive regulation of dopamine secretion. Located in several cellular components, including endoplasmic reticulum; myelin sheath; and neuronal cell body. Is integral component of endoplasmic reticulum membrane. Part of protein-containing complex. Is active in glutamatergic synapse. Is integral component of postsynaptic density membrane. Biomarker of visual epilepsy. Orthologous to human RTN4 (reticulon 4). [provided by Alliance of Genome Resources, Apr 2022] |
synonyms |
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Properties | |