Protein Name membrane-spanning 4-domains, subfamily A, member 1
Organism Mus musculus
Gene ID 12482
Gene Symbol

Ms4a1

UniProt P19437 (CD20_MOUSE), Q542S5 (Q542S5_MOUSE)
Relationships Total Number of functionally related compound(s) : 88
Total Number of Articles : 76
Description

membrane-spanning 4-domains, subfamily A, member 1

Gene Summary

Predicted to enable epidermal growth factor receptor binding activity; identical protein binding activity; and immunoglobulin binding activity. Involved in positive regulation of calcium ion import across plasma membrane. Acts upstream of or within response to bacterium. Located in external side of plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Human ortholog(s) of this gene implicated in common variable immunodeficiency 5. Orthologous to human MS4A1 (membrane spanning 4-domains A1). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • B-lymphocyte antigen CD20
  • B-cell differentiation antigen Ly-44
  • CD20 antigen
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Properties