Protein Name C-C motif chemokine receptor 5
Organism Rattus norvegicus
Gene ID 117029
Gene Symbol

Ccr5

UniProt O08556 (CCR5_RAT), Q68G28 (Q68G28_RAT)
Relationships Total Number of functionally related compound(s) : 59
Total Number of Articles : 44
Description

C-C motif chemokine receptor 5

Gene Summary

Enables protein kinase binding activity. Involved in several processes, including nervous system development; positive regulation of cytokine production; and response to bacterium. Located in cell surface and endosome. Used to study Alzheimer's disease; plague; and visual epilepsy. Biomarker of several diseases, including artery disease (multiple); diabetes mellitus (multiple); end stage renal disease; orchitis; and uveitis (multiple). Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease; West Nile fever; autoimmune disease (multiple); berylliosis; and sarcoidosis (multiple). Orthologous to human CCR5 (C-C motif chemokine receptor 5). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • C-C chemokine receptor type 5
  • C-C CKR-5
  • CC-CKR-5
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Properties