Protein Name zinc finger E-box binding homeobox 1
Organism Homo sapiens
Gene ID 6935
Gene Symbol

ZEB1

UniProt P37275 (ZEB1_HUMAN), B2RBI8 (B2RBI8_HUMAN), B4DGU2 (B4DGU2_HUMAN)
Relationships Total Number of functionally related compound(s) : 302
Total Number of Articles : 404
Description

zinc finger E-box binding homeobox 1

Gene Summary

This gene encodes a zinc finger transcription factor. The encoded protein likely plays a role in transcriptional repression of interleukin 2. Mutations in this gene have been associated with posterior polymorphous corneal dystrophy-3 and late-onset Fuchs endothelial corneal dystrophy. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Mar 2010]

synonyms
  • zinc finger E-box-binding homeobox 1
  • delta-crystallin enhancer binding factor 1
  • negative regulator of IL2
Click to show/hide the synonyms
Properties