| Protein Name | interleukin 33 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 77125 |
| Gene Symbol | Il33 |
| UniProt | Q8BVZ5 (IL33_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
281
Total Number of Articles : 328 |
Description |
interleukin 33 |
| Gene Summary |
Enables cytokine activity and interleukin-33 receptor binding activity. Involved in several processes, including interleukin-33-mediated signaling pathway; microglial cell activation involved in immune response; and regulation of gene expression. Acts upstream of or within several processes, including negative regulation of macrophage proliferation; positive regulation of cellular defense response; and positive regulation of macromolecule metabolic process. Located in nucleus. Is expressed in several structures, including adrenal gland; alimentary system; genitourinary system; nervous system; and sensory organ. Used to study Alzheimer's disease. Human ortholog(s) of this gene implicated in candidiasis; inflammatory bowel disease; and peptic ulcer disease. Orthologous to human IL33 (interleukin 33). [provided by Alliance of Genome Resources, Apr 2022] |
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