Protein Name hexokinase 1
Organism Homo sapiens
Gene ID 3098
Gene Symbol


UniProt P19367 (HXK1_HUMAN), A0A024QZK7 (A0A024QZK7_HUMAN), P78542 (P78542_HUMAN), B3KXY9 (B3KXY9_HUMAN), A8K7J7 (A8K7J7_HUMAN), Q59FD4 (Q59FD4_HUMAN)
Relationships Total Number of functionally related compound(s) : 604
Total Number of Articles : 1021

hexokinase 1

Gene Summary

Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in several transcript variants which encode different isoforms, some of which are tissue-specific. [provided by RefSeq, Apr 2016]

  • hexokinase-1
  • Neuropathy, hereditary motor and sensory, Russe type
  • brain form hexokinase
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