Protein Name potassium inwardly-rectifying channel, subfamily J, member 2
Organism Mus musculus
Gene ID 16518
Gene Symbol

Kcnj2

UniProt P35561 (KCNJ2_MOUSE), Q543W5 (Q543W5_MOUSE)
Relationships Total Number of functionally related compound(s) : 56
Total Number of Articles : 58
Description

potassium inwardly-rectifying channel, subfamily J, member 2

Gene Summary

Enables identical protein binding activity. Acts upstream of or within cardiac muscle cell action potential and magnesium ion transport. Predicted to be located in several cellular components, including T-tubule; endoplasmic reticulum; and intercalated disc. Predicted to be intrinsic component of membrane. Predicted to be part of voltage-gated potassium channel complex. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; heart; and sensory organ. Human ortholog(s) of this gene implicated in Andersen-Tawil syndrome; familial atrial fibrillation; familial periodic paralysis; and short QT syndrome. Orthologous to human KCNJ2 (potassium inwardly rectifying channel subfamily J member 2). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • inward rectifier potassium channel 2
  • IRK-1
  • inward rectifier K(+) channel Kir2.1
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Properties